Ongoing Research Projects

• Cloning, expression, isolation and purification of papain gene/product for commercial production.
• Cloning, expression, and purification of caspase 3 gene and its use as vaccine against certain type of cancers.
• Use of receptor mediated liposomes as a drug delivery methods against cancer cell lines.
• Preparation of chimeric human antibodies for the prevention of AIDS.
• Propagation of Cordyceps sinensis on alternative substrates and extraction of cordycepin on commercial basis.
• Determination of CYP2C19 polymorphism associated with Clopidogrel metabolism to investigate pharmacogenomics of Clopidogrel in patients with acute coronary syndrome, atherosclerotic vascular disease and atrial fibrillation.
• Detection of Beta thalassemia by development of commercial viable kit through LAMP technique.
• Site specific mutagenesis in different vector’s promoters to enhance the expression of genes.
• Development of techniques for commercial production of Taq DNA polymerase, T-4 DNA ligase, and Reverse transcriptase enzymes.
• Development and validation of Quantitative Real Time PCR methodologies for Viral Load assessment of HBV, HIV etc.
• Development of Quantitative and Relative Quantitative Real Time PCR methodologies for Gene Expression analysis.
• Development of end point PCR based technique for cross contamination detection in human, rat, mouse and Chinese hamster cell.
• Estimation of nutrients level in various mushroom via HPLC.
• Enrichment of vit D in various mushroom species for pharmaceutical purpose.
• Study of Antimicrobial efficacy of herbal plants extracts on plant pathogens, to develop environment friendly methods for treatment of plant disease.
• Study of Antimicrobial efficacy of herbal plants extracts & MIC on pathogens causing various human disease.
• Plant tissue culture of Horticulture plants ,Bamboo & Hemp.
• Mycoremediation.
• Isolation and amplification of gene R.BamHI from Bacillus amyloliquefuciens using specific primers (primers with restriction sites and poly-His tags) followed by cloning into pPicZαA vector using EcoRI and NotI Restriction Enzyme in E. coli.
• Development of protocols for increasing production of exotic mushroom species.
• Study of antimicrobial property of exotic mushrooms.
• Development & standardisation of methods for the removal & control contaminants affecting the mushroom cultivation.